Miami to Panama City

Panama Potpourri

fares from $3,199 per guest

10-Day Voyage

Sirena

Special Offer

Receive more luxury for less with up to a 4 Category Upgrade* plus simply MORE with 2 for 1 Cruise Fares and:

FREE $600 simply MORE Shore Excursion Credit
FREE Champagne, Wine & More
FREE Gourmet Specialty Dining
FREE Unlimited WiFi
Amenities are per stateroom

Book Now - Offer ends September 30, 2024

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You probably can’t think of Panama City without conjuring images of the Panama Canal. But nearly 400 years before the Panama Canal opened its locks, Panama City was making its mark. From the vestiges of the original settlement to the modern skyscrapers, experience the history and culture of one of the Pacific Coast’s oldest continuously inhabited European settlements. After exploring the bustling local markets in search of fresh fish or artisan handicrafts, admire the restored Spanish Colonial architecture in Casco Viejo. Or you can head to the Miraflores Locks and watch one of the modern world’s most heroic feats of engineering in action.